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本帖最后由 orionsnow 于 2009-8-8 23:53 编辑
或者应该是量子统计基因组学?
或者 基因组统计学?
后边这2个名字是我自己想的,也不知道是不是合适。
第0篇
量子li学入门。
http://www.dolc.de/forum/viewthread.php?tid=984104
基因组学入门。
第一篇,
量子力学在生物学中的作用不平凡么?
Does quantum mechanics play a non-trivial role in life?
P.C.W. Davies
Australian Centre for Astrobiology, Macquarie University, New South Wales, 2109, Australia
Abstract
There have been many claims that quantum mechanics plays a key role in the origin and/or operation of biological organisms,
beyond merely providing the basis for the shapes and sizes of biological molecules and their chemical affinities. These range
from Schr¨odinger’s suggestion that quantum fluctuations produce mutations, to Hameroff and Penrose’s conjecture that quantum
coherence in microtubules is linked to consciousness. I review some of these claims in this paper, and discuss the serious problem
of decoherence. I advance some further conjectures about quantum information processing in bio-systems. Some possible
experiments are suggested.
© 2004 Elsevier Ireland Ltd. All rights reserved.
Keywords: Molecular biology; Quantum computing; Quantum information; Decoherence; Biophysics
http://cosmos.asu.edu/publicatio ... Systems%20paper.pdf
第一部分找到点新资料,大概意思是说, 物理+生物, 是目前物理学研究的一个挑战,我补充到首页里头去了。
http://wwwcp.tphys.uni-heidelberg.de/challenges/index.php
和我的思路有点远,不过和老太爷的思路有点像,就是从正面推进过去的,也取得了不少成果,也是海德堡大学物理系做的。
Since some time the science community has singled out the grand challenges that science is facing. There are from the fields
* Quantum Chromo Dynamics,
* Biophysics,
* Astrophysics and
* Materials Science
Among them are challenges that cross the border between physics and biology. Due to the vast amount of data that is now available there is the possibility to understand living organisms as complex dynamic systems and to simulate their behavior. Biological processes occur on a wide range of spatial and temporal scales. The time scales of biological function range from very fast femtosecond molecular motions, to multi second protein folding pathways, to cell cycle and development processes that take place over the order of minutes, hours and days. Similarly, the dimensions of biological interest range from small organic molecules to multi-protein complexes, to cellular processes, to tissues, to the interaction of human populations with the environment. Thus one needs to understand how on the smallest scale conformational changes of molecules plus their interaction give rise to collective phenomena. Modelling the complex biological system is one of the greatest challenges due to the levels and scales involved. Physics can make a contribution leading to fundamental insights due to its tradition in modelling complex systems and its mathematical framework and computational approaches. Methods and theories from physics provide the tools and language of molecular structure from the smallest to the largest molecules and the fundamental laws to explain how molecules interact and form their three-dimensional shape.
If particular, todays grand challenges are:
* the relationship between structure of molecules and high level complexes of molecules and their function (for example: What is the structure of the DNA in the nucleus and how does this structure govern DNA transcription; given the protein structure, what is its function)
* protein structure and function (for example structure prediction; RNA structure prediction and DNA and RNA interactions with proteins)
* cellular processes, mediated by interactions of signaling molecules and their cell surface receptors
* biofluid dynamics
* how does behavior emerge from properties of neurons and networks of neurons
* what factors maintain biodiversity?
Common to these problems is the need for a theory for systems that combine stochastic and nonlinear effects, often in partially distributed systems.
第二部分
某些生命是不违反热力学第二定律?
(有争议话题) |
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